Open AccessIntegration of Germline Pharmacogenetics Into a Tumor Sequencing Program
Author(s) -
Daniel L. Hertz,
Andrew C. Glatz,
Amy L Pasternak,
Robert J. Lonigro,
Pankaj Vats,
YiMi Wu,
Bailey Anderson,
Erica Rabban,
Erika Mora,
Kevin Frank,
Dan R. Robinson,
Rajen Mody,
Arul M. Chinnaiyan
Publication year - 2018
Publication title -
jco precision oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.405
H-Index - 22
ISSN - 2473-4284
DOI - 10.1200/po.18.00011
Subject(s) - dpyd , germline , pharmacogenomics , genotyping , medicine , pharmacogenetics , oncology , genotype , genetic testing , germline mutation , genetics , pharmacology , biology , mutation , gene
Evidence-based guidelines inform treatment decisions for patients for whom germline genetic information is available. Our real-time tumor sequencing program, which makes precision treatment decisions for patients with cancer, produces matched germline information, providing a unique opportunity to efficiently implement pharmacogenetics and benefit patients.