Integration of Germline Pharmacogenetics Into a Tumor Sequencing Program
Author(s) -
Daniel L. Hertz,
Andrew C. Glatz,
Amy L. Pasternak,
Robert J. Lonigro,
Pankaj Vats,
YiMi Wu,
Bailey Anderson,
Erica Rabban,
Erika Mora,
Kevin Frank,
Dan R. Robinson,
Rajen Mody,
Arul M. Chinnaiyan
Publication year - 2018
Publication title -
jco precision oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.405
H-Index - 22
ISSN - 2473-4284
DOI - 10.1200/po.18.00011
Subject(s) - dpyd , germline , pharmacogenomics , genotyping , medicine , pharmacogenetics , oncology , genotype , genetic testing , germline mutation , genetics , pharmacology , biology , mutation , gene
Evidence-based guidelines inform treatment decisions for patients for whom germline genetic information is available. Our real-time tumor sequencing program, which makes precision treatment decisions for patients with cancer, produces matched germline information, providing a unique opportunity to efficiently implement pharmacogenetics and benefit patients.
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