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OncoKB: A Precision Oncology Knowledge Base
Author(s) -
Debyani Chakravarty,
Jianjiong Gao,
Sarah Phillips,
Ritika Kundra,
Hongxin Zhang,
Jiaojiao Wang,
Julia E. Rudolph,
Rona Yaeger,
Tara E. Soumerai,
Moriah H. Nissan,
Matthew T. Chang,
Sarat Chandarlapaty,
Tiffany A. Traina,
Paul K. Paik,
Alan L. Ho,
Feras M. Hantash,
Andrew Grupe,
Shrujal S. Baxi,
Margaret K. Callahan,
Alexandra Snyder,
Ping Chi,
Daniel C. Danila,
Mrinal M. Gounder,
James J. Harding,
Matthew D. Hellmann,
Gopa Iyer,
Yelena Y. Janjigian,
Thomas J. Kaley,
Douglas A. Levine,
Maeve A. Lowery,
Antonio Omuro,
Michael A. Postow,
Dana E. Rathkopf,
Alexander N. Shoushtari,
Neerav Shukla,
Martin H. Voss,
Ederlinda Paraiso,
Ahmet Zehir,
Michael F. Berger,
Barry S. Taylor,
Leonard Saltz,
Gregory J. Riely,
Marc Ladanyi,
David M. Hyman,
José Baselga,
Paul Sabbatini,
David B. Solit,
Nikolaus Schultz
Publication year - 2017
Publication title -
jco precision oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.405
H-Index - 22
ISSN - 2473-4284
DOI - 10.1200/po.17.00011
Subject(s) - precision oncology , precision medicine , medicine , disease , cancer , genomics , oncology , computational biology , bioinformatics , biology , gene , genome , pathology , genetics
With prospective clinical sequencing of tumors emerging as a mainstay in cancer care, there is an urgent need for a clinical support tool that distills the clinical implications associated with specific mutation events into a standardized and easily interpretable format. To this end, we developed OncoKB, an expert-guided precision oncology knowledge base.

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