Open AccessInherited Mutations in Men Undergoing Multigene Panel Testing for Prostate Cancer: Emerging Implications for Personalized Prostate Cancer Genetic Evaluation
Author(s) -
Veda N. Giri,
Elias Obeid,
Laura Gross,
Lisa Bealin,
Colette Hyatt,
Sarah Hegarty,
Susan Montgomery,
Andrea Forman,
Ruth Bingler,
William Kevin Kelly,
Adam P. Dicker,
Stephanie Winheld,
Edouard J. Trabulsi,
David Y.T. Chen,
Costas D. Lallas,
Brian Allen,
Mary B. Daly,
Leonard G. Gomella
Publication year - 2017
Publication title -
jco precision oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.405
H-Index - 22
ISSN - 2473-4284
DOI - 10.1200/po.16.00039
Subject(s) - prostate cancer , genetic testing , oncology , medicine , cancer , genetic counseling , breast cancer , bioinformatics , genetics , biology
Multigene panels are commercially available for the evaluation of prostate cancer (PCA) predisposition, which necessitates tailored genetic counseling (GC) for men. Here we describe emerging results of Genetic Evaluation of Men, prospective multigene testing study in PCA to inform personalized genetic counseling, with emerging implications for referrals, cancer screening, and precision therapy.