Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer | Zendy

Benjamin W. Deschner | Zendy; Noam A. VanderWalde | Zendy; Axel Grothey | Zendy; David Shibata | Zendy

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Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer

Author(s) -

Benjamin W. Deschner,

Noam A. VanderWalde,

Axel Grothey,

David Shibata

Publication year - 2021

Publication title -

jco oncology practice

Language(s) - English

Resource type - Journals

eISSN - 2688-1535

pISSN - 2688-1527

DOI - 10.1200/op.20.00885

Subject(s) - multidisciplinary approach , paradigm shift , context (archaeology) , colorectal cancer , malignancy , medicine , intensive care medicine , cancer , geography , sociology , social science , philosophy , archaeology , epistemology

The management of locally advanced rectal cancer has grown in both complexity and quality since the first proctectomy. What once was a malignancy with a fairly consistent treatment algorithm for decades, a recent paradigm shift in the care of these patients has led to a more personalized, multidisciplinary approach with variations in timing, sequence, duration, and potential exclusion of multimodality therapies. This review summarizes the most important evidence behind these developing overarching concepts to provide a context for this paradigm shift.

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