Multimodality Therapy for Limited-Stage Small-Cell Lung Cancer
Author(s) -
Daniel Almquist,
Kailash Mosalpuria,
Apar Kishor Ganti
Publication year - 2016
Publication title -
journal of oncology practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.555
H-Index - 60
eISSN - 1935-469X
pISSN - 1554-7477
DOI - 10.1200/jop.2015.009068
Subject(s) - medicine , radiation therapy , stage (stratigraphy) , prophylactic cranial irradiation , disease , small cell lung carcinoma , chemotherapy , oncology , lung cancer , small cell carcinoma , paleontology , myocardial infarction , conventional pci , biology
Limited-stage small-cell lung cancer (SCLC) occurs in only one third of patients with SCLC, but it is potentially curable. Combined-modality therapy (chemotherapy and radiotherapy) has long been the mainstay of therapy for this condition, but more recent data suggest a role for surgery in early-stage disease. Prophylactic cranial irradiation seems to improve outcomes in patients who have responded to initial therapy. This review addresses the practical aspects of staging and treatment of patients with limited-stage SCLC.
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