
Prediagnostic Intervals in Retinoblastoma: Experience at an Oncology Center in Brazil
Author(s) -
Clarissa Mattosinho,
Nathália Grigorovski,
Evandro Lucena,
Sima Ester Ferman,
Anna Tereza Miranda Soares de Moura,
Arlindo Freire Portes
Publication year - 2017
Publication title -
journal of global oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.002
H-Index - 17
ISSN - 2378-9506
DOI - 10.1200/jgo.2016.005595
Subject(s) - medicine , retinoblastoma , stage (stratigraphy) , pediatrics , malignancy , univariate analysis , multivariate analysis , medical record , confidence interval , surgery , paleontology , biochemistry , chemistry , gene , biology
Retinoblastoma is the most common intraocular malignancy of childhood. In most cases, parents are the first to notice leukocoria and other symptoms before undergoing a prolonged period of stress before diagnosis. The purpose of this study was to determine prediagnostic intervals of patients with retinoblastoma at an oncology tertiary center (Instituto Nacional de Cancer) in Rio de Janeiro, Brazil, and relate them to stage at diagnosis, eye salvage, and survival.