Open AccessRegular Low-Dose Oral Metronidazole Is Associated With Fewer Vesicovaginal and Rectovaginal Fistulae in Recurrent Cervical Cancer: Results From a 10-Year Retrospective Cohort
Author(s) -
Reena George,
Thotampuri Shanthi Prasoona,
Ramu Kandasamy,
Thenmozhi Mani,
Shakila Murali,
R. Rekha,
Jayaprakash Muliyil
Publication year - 2019
Publication title -
journal of global oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.002
H-Index - 17
ISSN - 2378-9506
DOI - 10.1200/jgo.19.00206
Subject(s) - medicine , metronidazole , hazard ratio , interquartile range , retrospective cohort study , cervical cancer , surgery , proportional hazards model , rectovaginal fistula , vesicovaginal fistula , fistula , cohort , cancer , antibiotics , confidence interval , microbiology and biotechnology , biology
Anaerobic necrosis in cervical cancer can lead to malodor, fistulae, and treatment abandonment. In this retrospective cohort study, we examined the association between maintenance metronidazole and the incidence of malignant fistulae in recurrent cervical cancer.