Open AccessRandomized Phase II Trial to Compare the Efficacy of Haloperidol and Olanzapine in the Control of Chemotherapy-Induced Nausea and Vomiting in Nepal
Author(s) -
Soniya Dulal,
Bishnu Dutta Paudel,
Prakash Neupane,
Aarati Shah,
Bharat Sharma Acharya,
Bishesh Sharma Poudyal,
Ramila Shilpakar,
Lori Wood
Publication year - 2019
Publication title -
journal of global oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.002
H-Index - 17
ISSN - 2378-9506
DOI - 10.1200/jgo.18.00245
Subject(s) - olanzapine , nausea , medicine , vomiting , randomized controlled trial , haloperidol , chemotherapy induced nausea and vomiting , chemotherapy , dopamine antagonist , psychiatry , antiemetic , schizophrenia (object oriented programming) , dopamine
The purpose of the study was to compare efficacy and toxicity of olanzapine (OLN; a higher-cost drug) and haloperidol (HAL; a lower-cost drug) in the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients who receive highly emetogenic chemotherapy (HEC).