Circulating Tumor DNA and Late Recurrence in High-Risk Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer
Author(s) -
Marla Lipsyc-Sharf,
Elza C. de Bruin,
Katheryn Santos,
Robert McEwen,
Daniel Stetson,
Ashka Patel,
Gregory J. Kirkner,
Melissa E. Hughes,
Sara M. Tolaney,
Ann H. Partridge,
Ian E. Krop,
Charlene Knape,
Ute Feger,
Giovanni Marsico,
Karen Howarth,
Eric P. Winer,
Nancy U. Lin,
Heather A. Parsons
Publication year - 2022
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.22.00908
Subject(s) - medicine , breast cancer , oncology , cancer , minimal residual disease , hormone receptor , primary tumor , stage (stratigraphy) , prospective cohort study , metastasis , paleontology , leukemia , biology
To examine the prevalence and dynamics of circulating tumor DNA (ctDNA) and its association with metastatic recurrence in patients with high-risk early-stage hormone receptor-positive breast cancer (HR+ BC) more than 5 years from diagnosis.
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