A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma
Author(s) -
Simon J. Crabb,
Syed A. Hussain,
Eileen Soulis,
Samantha Hinsley,
Laura Dempsey,
Avril Trevethan,
YeePei Song,
Jim Barber,
J. Frew,
Joanna Gale,
Guy Faust,
Susannah Brock,
Ursula McGovern,
Omi Parikh,
Deborah Enting,
Santhanam Sundar,
Gihan Ratnayake,
Kathryn Lees,
Alison Birtle,
Thomas Powles,
Robert J. Jones
Publication year - 2022
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.22.00405
Subject(s) - medicine , hazard ratio , parp inhibitor , biomarker , placebo , chemotherapy , population , oncology , clinical endpoint , progression free survival , cancer , adverse effect , metastatic urothelial carcinoma , gastroenterology , surgery , randomized controlled trial , poly adp ribose polymerase , pathology , bladder cancer , confidence interval , biology , biochemistry , alternative medicine , environmental health , polymerase , gene , urothelial carcinoma
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