Open AccessPhysiologic Frailty and Neurocognitive Decline Among Young-Adult Childhood Cancer Survivors: A Prospective Study From the St Jude Lifetime Cohort
Author(s) -
AnnaLynn M. Williams,
Kevin R. Krull,
Carrie R. Howell,
Pia Banerjee,
Tara M. Brinkman,
Sue C. Kaste,
Robyn E. Partin,
Deokumar Srivastava,
Yutaka Yasui,
Gregory T. Armstrong,
Leslie L. Robison,
Melissa M. Hudson,
Kirsten K. Ness
Publication year - 2021
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.21.00194
Subject(s) - medicine , neurocognitive , cohort , population , prospective cohort study , pediatrics , gerontology , physical therapy , cognition , psychiatry , environmental health
Eight percent of young-adult childhood cancer survivors meet criteria for frailty, an aging phenotype associated with poor health. In the elderly general population, frailty is associated with neurocognitive decline; this association has not been examined in adult survivors of childhood cancer.