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Stem-Cell Transplantation in Children With Acute Lymphoblastic Leukemia: A Prospective International Multicenter Trial Comparing Sibling Donors With Matched Unrelated Donors—The ALL-SCT-BFM-2003 Trial
Author(s) -
Christina Peters,
Martin Schrappe,
Arend von Stackelberg,
André Schrauder,
Peter Bader,
Wolfram Ebell,
Peter Lang,
KarlWalter Sykora,
Johanna Schrum,
Bernhard Kremens,
Karoline Ehlert,
Michael H. Albert,
Roland Meisel,
Susanne MatthesMartin,
Tayfun Güngör,
Wolfgang Holter,
Brigitte Strahm,
Bernd Gruhn,
Ansgar Schulz,
Wilhelm Woessmann,
Ulrike Pöetschger,
Martin Zimmermann,
Thomas Klingebiel
Publication year - 2015
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2014.58.9747
Subject(s) - medicine , transplantation , cumulative incidence , hematopoietic stem cell transplantation , total body irradiation , acute lymphocytic leukemia , bone marrow , stem cell , leukemia , oncology , surgery , immunology , cyclophosphamide , chemotherapy , lymphoblastic leukemia , biology , genetics
Although hematopoietic stem-cell transplantation is widely performed in children with high-risk acute lymphoblastic leukemia (ALL), the influence of donor types is poorly understood. Thus, transplantation outcomes were compared in the prospective multinational Berlin-Frankfurt-Muenster (BFM) study group trial: ALL-SCT-BFM 2003 (Allogeneic Stem Cell Transplantation in Children and Adolescents with Acute Lymphoblastic Leukemia).

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