Prostate Cancer: Evolution or Revolution?

In this issue of Journal of Clinical Oncology, we present a special series on prostate cancer that illustrates how our understanding of the biology and therapy of this disease has changed over the last few years. This series comes on the heels of the 2011 Genitourinary Cancers Symposium (held February 17 to 19, 2011, in Orlando, FL), jointly sponsored by the American Society of Clinical Oncology, the American Society for Therapeutic and Radiation Oncology, and the Society of Urologic Oncology. It is instructive to consider how the field has evolved, as articulated in the review articles in this issue, compared with the state of the art described in a special edition of the Journal published shortly after the first Prostate Cancer Symposium in 2005.