Primary Melanoma of the Spinal Cord: A Case Report, Molecular Footprint, and Review of the Literature | Zendy

Alexander D. Fuld | Zendy; Maren E. Speck | Zendy; Brent T. Harris | Zendy; Nathan E. Simmons | Zendy; Christopher L. Corless | Zendy; Gregory J. Tsongalis | Zendy; David A. Pastel | Zendy; Alan C. Hartford | Zendy; Marc S. Ernstoff | Zendy

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Primary Melanoma of the Spinal Cord: A Case Report, Molecular Footprint, and Review of the Literature

Author(s) -

Alexander D. Fuld,

Maren E. Speck,

Brent T. Harris,

Nathan E. Simmons,

Christopher L. Corless,

Gregory J. Tsongalis,

David A. Pastel,

Alan C. Hartford,

Marc S. Ernstoff

Publication year - 2011

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2010.34.0695

Subject(s) - medicine , footprint , melanoma , spinal cord , pathology , dermatology , cancer research , paleontology , psychiatry , biology

Primary melanoma of the spinal cord is a rare entity with fewer than 60 cases reported in the literature since the first report in 1906. The diagnosis requires exclusion of a primary cutaneous or ocular lesion, as in rare instances melanoma may metastasize to the spinal cord. Prognosis is generally better, with a slower rate of progression, than for cutaneous melanoma with CNS metastases. We report a case of this uncommon tumor and also describe the molecular footprint that characterizes it.

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