Body Mass Index Increases Risk of Colorectal Adenomas in Men With Lynch Syndrome: The GEOLynch Cohort Study
Author(s) -
Akke Botma,
Fokko M. Nagengast,
Marieke G. M. Braem,
Jan C.M. Hendriks,
Jan H. Kleibeuker,
Hans F. A. Vasen,
Ellen Kampman
Publication year - 2010
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2010.28.0453
Subject(s) - medicine , body mass index , hazard ratio , overweight , cohort , colorectal cancer , prospective cohort study , cohort study , risk factor , proportional hazards model , colorectal adenoma , gastroenterology , cancer , confidence interval
High body mass index (BMI) is an established risk factor for sporadic colorectal cancer. Still, the influence of BMI on hereditary colorectal cancer (eg, Lynch syndrome [LS]), is unknown. The objective of this study was to assess whether BMI is associated with colorectal adenoma occurrence in persons with LS.
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