Population-Based Study of the Risk of Second Primary Contralateral Breast Cancer Associated With Carrying a Mutation in BRCA1 or BRCA2
Author(s) -
Kathleen E. Malone,
Colin B. Begg,
Robert W. Haile,
Åke Borg,
Patrick Concan,
Lina Tellhed,
Shanyan Xue,
Sharon N. Teraoka,
Leslie Bernstein,
Marinela Capanu,
Anne S. Reiner,
Elyn Riedel,
Duncan C. Thomas,
Lene Mellemkjær,
Charles F. Lynch,
John D. Boice,
Hoda AntonCulver,
Jonine L. Bernstein
Publication year - 2010
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2009.24.2495
Subject(s) - medicine , breast cancer , oncology , mutation , population , cancer , gynecology , genetics , environmental health , gene , biology
Women with breast cancer diagnosed early in life comprise a substantial portion of those tested for BRCA1/BRCA2 mutations; however, little information is available on the subsequent risks of contralateral breast cancer in mutation carriers. This study assessed the risk of subsequent contralateral breast cancer associated with carrying a BRCA1 or BRCA2 mutation.
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