Identification and Validation of a Gene Expression Signature That Predicts Outcome in Adult Men With Germ Cell Tumors | Zendy

James E. Korkola | Zendy; Jane Houldsworth | Zendy; Darren R. Feldman | Zendy; Adam B. Olshen | Zendy; Li-Xuan Qin | Zendy; Sujata Patil | Zendy; Victor E. Reuter | Zendy; George J. Bosl | Zendy; R. S. K. Chaganti | Zendy

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Identification and Validation of a Gene Expression Signature That Predicts Outcome in Adult Men With Germ Cell Tumors

Author(s) -

James E. Korkola,

Jane Houldsworth,

Darren R. Feldman,

Adam B. Olshen,

Li-Xuan Qin,

Sujata Patil,

Victor E. Reuter,

George J. Bosl,

R. S. K. Chaganti

Publication year - 2009

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2008.20.0386

Subject(s) - medicine , concordance , oncology , univariate , germ cell tumors , proportional hazards model , gene expression profiling , univariate analysis , malignancy , survival analysis , gene signature , multivariate analysis , gene expression , gene , multivariate statistics , biology , machine learning , biochemistry , chemotherapy , computer science

Germ cell tumor (GCT) is the most common malignancy in young adult men. Currently, patients are risk-stratified on the basis of clinical presentation and serum tumor markers. The introduction of molecular markers could improve outcome prediction.

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