Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases
Author(s) -
Susan B. Kesmodel,
Lee M. Ellis,
E. Lin,
George J. Chang,
Eddie K. Abdalla,
Scott Kopetz,
JeanNicolas Vauthey,
Miguel A. Rodrı́guez-Bigas,
Steven A. Curley,
Barry W. Feig
Publication year - 2008
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2008.17.7857
Subject(s) - medicine , bevacizumab , colorectal cancer , discontinuation , complication , surgery , neoadjuvant therapy , univariate analysis , chemotherapy , logistic regression , concomitant , multivariate analysis , cancer , breast cancer
Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase in wound complications has been observed in patients who undergo surgery while receiving BV. We therefore evaluated whether neoadjuvant BV is associated with an increase in postoperative complications in patients undergoing surgery for CRC liver metastases.
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