Open AccessNatural History of CNS Relapse in Patients With Aggressive Non-Hodgkin's Lymphoma: A 20-Year Follow-Up Analysis of SWOG 8516—The Southwest Oncology Group
Author(s) -
Steven H. Bernstein,
Joseph M. Unger,
Michael LeBlanc,
Jonathan W. Friedberg,
Thomas P. Miller,
Richard I. Fisher
Publication year - 2009
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2008.16.8021
Subject(s) - medicine , vincristine , cyclophosphamide , international prognostic index , aggressive lymphoma , etoposide , prednisone , cumulative incidence , oncology , chemotherapy , lymphoma , surgery , rituximab , cohort
To investigate the incidence, natural history, and risk factors predictive of CNS relapse in patients with de novo aggressive lymphomas and to evaluate the efficacy of CNS prophylaxis in patients with initial bone marrow (BM) involvement.