Predominant Treatment Failure in Postprostatectomy Patients Is Local: Analysis of Patterns of Treatment Failure in SWOG 8794 | Zendy

Gregory P. Swanson | Zendy; Michael A. Hussey | Zendy; Catherine M. Tangen | Zendy; Joseph L. Chin | Zendy; Edward M. Messing | Zendy; Edith CanbyHagino | Zendy; Jeffrey D. Forman | Zendy; Ian M. Thompson | Zendy; E. David Crawford | Zendy

Open Access

Predominant Treatment Failure in Postprostatectomy Patients Is Local: Analysis of Patterns of Treatment Failure in SWOG 8794

Author(s) -

Gregory P. Swanson,

Michael A. Hussey,

Catherine M. Tangen,

Joseph L. Chin,

Edward M. Messing,

Edith CanbyHagino,

Jeffrey D. Forman,

Ian M. Thompson,

E. David Crawford

Publication year - 2007

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2006.09.6495

Subject(s) - medicine , prostatectomy , prostate cancer , radiation therapy , prostate specific antigen , adjuvant , incidence (geometry) , urology , surgery , oncology , cancer , physics , optics

Southwest Oncology Group (SWOG) trial 8794 demonstrated that adjuvant radiation reduces the risk of biochemical (prostate-specific antigen [PSA]) treatment failure by 50% over radical prostatectomy alone. In this analysis, we stratified patients as to their preradiation PSA levels and correlated it with outcomes such as PSA treatment failure, local recurrence, and distant failure, to serve as guidelines for future research.

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