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Reclassification of 300 Primary Cutaneous B-Cell Lymphomas According to the New WHO–EORTC Classification for Cutaneous Lymphomas: Comparison With Previous Classifications and Identification of Prognostic Markers
Author(s) -
Nancy J. Senff,
Juliette J. Hoefnagel,
Patty M. Jansen,
Maarten H. Vermeer,
Joop van Baarlen,
Willeke A.M. Blokx,
Marijke R. Canningavan Dijk,
MarieLouise Geerts,
Konnie M. Hebeda,
Philip M. Kluin,
King H. Lam,
Chris J.L.M. Meijer,
Rein Willemze
Publication year - 2007
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2006.09.6396
Subject(s) - medicine , cbcl , lymphoma , oncology , cutaneous lymphoma , recursive partitioning , not otherwise specified , multivariate analysis , marginal zone , mycosis fungoides , pathology , b cell , immunology , antibody , clinical psychology
In the new WHO-European Organisation for Research and Treatment of Cancer (WHO-EORTC) classification for cutaneous lymphomas three major groups of primary cutaneous B-cell lymphoma (CBCL) are distinguished: primary cutaneous marginal zone B-cell lymphoma (PCMZL) and primary cutaneous follicle center lymphoma (PCFCL) with a good prognosis, and primary cutaneous large B-cell lymphoma, leg type (PCLBCL-LT), with an intermediate-level prognosis. This study aimed to assess the clinical significance of the new classification compared with previous classification schemes (EORTC 1997; WHO 2001) and to define prognostic factors within the newly defined categories.

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