Predicting the Outcome of Salvage Radiation Therapy for Recurrent Prostate Cancer After Radical Prostatectomy
Author(s) -
Andrew J. Stephenson,
Peter T. Scardino,
Michael W. Kattan,
Thomas M. Pisansky,
Kevin M. Slawin,
Eric A. Klein,
Mitchell S. Anscher,
Jeff M. Michalski,
Howard M. Sandler,
Daniel W. Lin,
Jeffrey D. Forman,
Michael J. Zeléfsky,
Larry L. Kestin,
Claus G. Roehrborn,
Charles Catton,
Theodore L. DeWeese,
Stanley L. Liauw,
Richard K. Valicenti,
Deborah A. Kuban,
Alan Pollack
Publication year - 2007
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2006.08.9607
Subject(s) - medicine , prostatectomy , nomogram , prostate cancer , androgen deprivation therapy , urology , biochemical recurrence , prostate specific antigen , radiation therapy , proportional hazards model , concordance , cancer , surgery , oncology
An increasing serum prostate-specific antigen (PSA) level is the initial sign of recurrent prostate cancer among patients treated with radical prostatectomy. Salvage radiation therapy (SRT) may eradicate locally recurrent cancer, but studies to distinguish local from systemic recurrence lack adequate sensitivity and specificity. We developed a nomogram to predict the probability of cancer control at 6 years after SRT for PSA-defined recurrence.
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