Phase III Trial Comparing 4-Day Chronomodulated Therapy Versus 2-Day Conventional Delivery of Fluorouracil, Leucovorin, and Oxaliplatin As First-Line Chemotherapy of Metastatic Colorectal Cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group | Zendy

Sylvie Giacchetti | Zendy; Georg A. Bjarnason | Zendy; Carlo Garufi | Zendy; Dominique Genet | Zendy; Stefano Iacobelli | Zendy; Marco Tampellini | Zendy; Rune Smaaland | Zendy; C. Focan | Zendy; Bruno Coudert | Zendy; Yves Humblet | Zendy; Jean Luc Ca | Zendy; Antoine Adenis | Zendy; Giovanni Lo Re | Zendy; Carlos Carvalho | Zendy; Johannes Schueller | Zendy; Nicole Anciaux | Zendy; M.A. Lentz | Zendy; Benoît Baron | Zendy; Thierry Gorlia | Zendy; Françis Lévi | Zendy

Open Access

Phase III Trial Comparing 4-Day Chronomodulated Therapy Versus 2-Day Conventional Delivery of Fluorouracil, Leucovorin, and Oxaliplatin As First-Line Chemotherapy of Metastatic Colorectal Cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group

Author(s) -

Sylvie Giacchetti,

Georg A. Bjarnason,

Carlo Garufi,

Dominique Genet,

Stefano Iacobelli,

Marco Tampellini,

Rune Smaaland,

C. Focan,

Bruno Coudert,

Yves Humblet,

Jean Luc Ca,

Antoine Adenis,

Giovanni Lo Re,

Carlos Carvalho,

Johannes Schueller,

Nicole Anciaux,

M.A. Lentz,

Benoît Baron,

Thierry Gorlia,

Françis Lévi

Publication year - 2006

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2006.06.1440

Subject(s) - oxaliplatin , medicine , fluorouracil , colorectal cancer , oncology , chemotherapy , phases of clinical research , cancer

In two previous randomized trials, the adjustment of chemotherapy delivery to circadian rhythms improved tolerability and anticancer activity compared with constant-rate infusion during 5 days in patients with metastatic colorectal cancer.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research