Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in PediatricKMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531
Author(s) -
Jessica A. Pollard,
Erin Guest,
Todd A. Alonzo,
Robert B. Gerbing,
Mike R. Loken,
Lisa Eidenschink Brodersen,
E. Anders Kolb,
Richard Aplenc,
Soheil Meshinchi,
Susana C. Raimondi,
Betsy Hirsch,
Alan S. Gamis
Publication year - 2021
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.20.03048
Subject(s) - medicine , gemtuzumab ozogamicin , oncology , overall survival , genetics , stem cell , cd34 , cd33 , biology
We investigated the impact of the CD33-targeted agent gemtuzumab ozogamicin (GO) on survival in pediatric patients with KMT2A -rearranged ( KMT2A -r) acute myeloid leukemia (AML) enrolled in the Children's Oncology Group trial AAML0531 (NCT01407757).
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