Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer | Zendy

Bhishamjit S. Chera | Zendy; Sunil Kumar | Zendy; Colette J. Shen | Zendy; Robert J. Amdur | Zendy; Roi Dagan | Zendy; Rebecca Green | Zendy; Emily C. Goldman | Zendy; Jared Weiss | Zendy; Juneko E. GrilleyOlson | Zendy; Shetal Patel | Zendy; Adam M. Zanation | Zendy; Trevor Hackman | Zendy; Jeff Blumberg | Zendy; Samip Patel | Zendy; Brian D. Thorp | Zendy; Mark C. Weissler | Zendy; Wendell G. Yarbrough | Zendy; Nathan Sheets | Zendy; William M. Mendenhall | Zendy; Xianming Tan | Zendy; Gaorav P. Gupta | Zendy

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Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer

Author(s) -

Bhishamjit S. Chera,

Sunil Kumar,

Colette J. Shen,

Robert J. Amdur,

Roi Dagan,

Rebecca Green,

Emily C. Goldman,

Jared Weiss,

Juneko E. GrilleyOlson,

Shetal Patel,

Adam M. Zanation,

Trevor Hackman,

Jeff Blumberg,

Samip Patel,

Brian D. Thorp,

Mark C. Weissler,

Wendell G. Yarbrough,

Nathan Sheets,

William M. Mendenhall,

Xianming Tan,

Gaorav P. Gupta

Publication year - 2020

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.19.02444

Subject(s) - medicine , biomarker , chemoradiotherapy , cancer , biopsy , clinical endpoint , surrogate endpoint , prospective cohort study , circulating tumor cell , oncology , gastroenterology , clinical trial , metastasis , biochemistry , chemistry

Plasma circulating tumor human papillomavirus DNA (ctHPVDNA) is a sensitive and specific biomarker of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC). We investigated whether longitudinal monitoring of ctHPVDNA during post-treatment surveillance could accurately detect clinical disease recurrence.

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