Ten-Year Update of a Randomized, Prospective Trial of Conventional Fractionated Versus Moderate Hypofractionated Radiation Therapy for Localized Prostate Cancer | Zendy

Vladimir Avkshtol | Zendy; Karen Ruth | Zendy; Eric A. Ross | Zendy; M.A. Hallman | Zendy; Richard E. Greenberg | Zendy; R Price | Zendy; Brooke K. Leachman | Zendy; Robert G. Uzzo | Zendy; Charlie Ma | Zendy; David Chen | Zendy; Daniel M. Geynisman | Zendy; Mark L. Sobczak | Zendy; Eddie Zhang | Zendy; Jessica Karen Wong | Zendy; Alan Pollack | Zendy; Eric M. Horwitz | Zendy

Open Access

Ten-Year Update of a Randomized, Prospective Trial of Conventional Fractionated Versus Moderate Hypofractionated Radiation Therapy for Localized Prostate Cancer

Author(s) -

Vladimir Avkshtol,

Karen Ruth,

Eric A. Ross,

M.A. Hallman,

Richard E. Greenberg,

R Price,

Brooke K. Leachman,

Robert G. Uzzo,

Charlie Ma,

David Chen,

Daniel M. Geynisman,

Mark L. Sobczak,

Eddie Zhang,

Jessica Karen Wong,

Alan Pollack,

Eric M. Horwitz

Publication year - 2020

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.19.01485

Subject(s) - medicine , prostate cancer , cumulative incidence , androgen deprivation therapy , radiation therapy , clinical endpoint , randomized controlled trial , prospective cohort study , incidence (geometry) , lymph node , cancer , surgery , cohort , physics , optics

The previously published single institution randomized prospective trial failed to show superiority in the 5-year biochemical and/or clinical disease failure (BCDF) rate with moderate hypofractionated intensity-modulated radiation therapy (H-IMRT) versus conventionally fractionated IMRT (C-IMRT). We now present 10-year disease outcomes using updated risk groups and definitions of biochemical failure.

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