Impact of Androgen Deprivation on Oxidative Stress and Antioxidant Status in Nigerian Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy | Zendy

Iya Eze Bassey | Zendy; Bukola Abosede Emodi | Zendy; Uwem Okon Akpan | Zendy; Idorenyin Francesca Akpan Iyakndue | Zendy; Edim Azubuike Anakebe | Zendy; Bassey Edward Icha | Zendy; Henry Afamuefuna Efobi | Zendy; Akan Joshua Ntinya | Zendy; A. E. Udoh | Zendy

Open Access

Impact of Androgen Deprivation on Oxidative Stress and Antioxidant Status in Nigerian Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy

Author(s) -

Iya Eze Bassey,

Bukola Abosede Emodi,

Uwem Okon Akpan,

Idorenyin Francesca Akpan Iyakndue,

Edim Azubuike Anakebe,

Bassey Edward Icha,

Henry Afamuefuna Efobi,

Akan Joshua Ntinya,

A. E. Udoh

Publication year - 2020

Publication title -

jco global oncology

Language(s) - English

Resource type - Journals

ISSN - 2687-8941

DOI - 10.1200/go.20.00290

Subject(s) - medicine , prostate cancer , malondialdehyde , androgen deprivation therapy , oxidative stress , gastroenterology , cancer , statistical significance , lipid profile , lipid peroxide , endocrinology , cholesterol , lipid peroxidation

Prostate cancer (CaP) incidence and mortality rate are increasing in Africa. Some have linked oxidative stress with the pathogenesis of cancer. This study assessed the levels of malondialdehyde (MDA), nitric oxide (NO), total plasma peroxide (TPP), and total antioxidant capacity (TAC) in Nigerian patients with CaP.

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