Diagnostic Performance of Indocyanine Green Plus Methylene Blue Versus Radioisotope Plus Methylene Blue Dye Method for Sentinel Lymph Node Biopsy in Node-Negative Early Breast Cancer
Author(s) -
Sanjit Kumar Agrawal,
Izideen Hashlamoun,
Banira Karki,
Abhishek Sharma,
Indu Arun,
Rosina Ahmed
Publication year - 2020
Publication title -
jco global oncology
Language(s) - English
Resource type - Journals
ISSN - 2687-8941
DOI - 10.1200/go.20.00165
Subject(s) - indocyanine green , medicine , sentinel lymph node , breast cancer , methylene blue , biopsy , lymph , nuclear medicine , gold standard (test) , cancer , radiology , surgery , pathology , chemistry , biochemistry , photocatalysis , catalysis
Sentinel lymph node biopsy (SLNB) by dual-dye method (radioisotope plus blue) is the gold standard for axillary staging in patients with breast cancer, but in developing countries, logistic issues and financial constraint play a vital role. Recently, indocyanine green (ICG) has emerged as an alternative to radioisotope (technetium-99 [Tc-99]) for SLNB in breast cancer. This study compared the diagnostic performance of Tc-99 plus methylene blue (MB) dye versus ICG + MB dye SLNB.
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