
Simulating Time-Dependent Patterns of Nonadherence by Patients With Breast Cancer to Adjuvant Oral Endocrine Therapy
Author(s) -
Eileen H. Shinn,
Gordon Broderick,
Bryan Fellman,
A R N Beth Johnson,
Elizabeth Wieland,
Stacy L. Moulder,
W. Fraser Symmans
Publication year - 2019
Publication title -
jco clinical cancer informatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.188
H-Index - 12
ISSN - 2473-4276
DOI - 10.1200/cci.18.00091
Subject(s) - discontinuation , medicine , breast cancer , adverse effect , worry , cancer , oncology , physical therapy , anxiety , psychiatry
Nearly 40% of patients with breast cancer discontinue their adjuvant oral endocrine treatment (ET). We measured discontinuation rates of ET at a comprehensive cancer center. We then used an iterative approach to model patterns of determinants associated with discontinuation of ET.