Premium
Etiology and Weekly Occurrence of Alcohol‐related Seizures
Author(s) -
Rathlev Niels K.,
Ulrich Andrew,
Shieh Ted C.,
Callum Michael G.,
Bernstein Edward,
D'Onofrio Gail
Publication year - 2002
Publication title -
academic emergency medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 124
eISSN - 1553-2712
pISSN - 1069-6563
DOI - 10.1197/aemj.9.8.824
Subject(s) - medicine , alcohol , etiology , alcohol dependence , alcohol withdrawal syndrome , convulsion , epilepsy , anesthesia , pediatrics , psychiatry , biochemistry , chemistry
Objectives: 1) To determine the prevalence of identifiable causes of alcohol‐related seizures other than alcohol withdrawal. 2) To test the hypothesis that patients with alcohol‐related seizures present with greater frequency following Sundays when alcohol is not commercially available. Methods: This was a retrospective chart review of 140 consecutive patients presenting with alcohol‐related seizures during a six‐month period. Identifiable causes of seizures other than alcohol withdrawal and the day of the week of presentation were documented. Results: One hundred forty individual patients were eligible for study. Identifiable causes of seizures other than alcohol withdrawal were found in 53.6% of patients, and they were distributed as follows: 1) current or past history of significant head trauma 25.7%, 2) idiopathic seizure disorder 15.7%, 3) cerebrovascular accident 5.7%, 4) nontraumatic intracranical lesion 3.6%, and 5) toxic/metabolic abnormalities 2.9%. Alcohol is not available for purchase on Sundays because of the “Blue Laws” in Massachusetts. A total of 34.5% of patients with alcohol withdrawal seizures presented on Mondays (p < 0.001). Of patients with identifiable causes of seizures other than alcohol withdrawal, only 16% presented on Mondays (p > 0.10). Conclusions: Approximately 50% of seizures in alcohol‐dependent patients are potentially unrelated to alcohol withdrawal. Patients with alcohol withdrawal seizures presented withgreater frequency on Mondays following the 24‐hour period when alcohol was not commercially available in Boston. This suggests that patients with alcohol withdrawal seizures may present with greater frequency following periods of decreased availability of alcohol.