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Bioinformatics and Transcriptomics Studies of Early Implantation
Author(s) -
Aplin John D.,
Singh Harmeet
Publication year - 2008
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1434.005
Subject(s) - transcriptome , computational biology , gene , endometrium , bioinformatics , biology , cell , microbiology and biotechnology , gene expression , genetics , endocrinology
Little is known of the genes that mediate cell interactions at implantation. A combined transcriptomics/bioinformatics protocol is described that identifies cell surface glycoproteins in endometrium with potential involvement in implantation. This is linked to an in vitro model in which functional assays of candidate gene products can be carried out.