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Comparison of the Molecular Structure of the TaSP Gene of Theileria annulata from Sudanese Isolates
Author(s) -
Ali Awadia M.,
Salih Diaeldin,
Bakheit Mohammed,
El Hussein Abdel Rahim M.,
Hassan Shawgi M.,
Mukhtar Maowia M.,
Ahmed Jabbar S.,
Seitzer Ulrike
Publication year - 2008
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1428.025
Subject(s) - parasite hosting , biology , gene , genetics , peptide sequence , virology , world wide web , computer science
The polymorphic region of the Theileria annulata surface protein ( Ta SP) was cloned and sequenced from different isolates of cattle and cell lines from different areas of Sudan. Amino acid sequence alignment revealed a high diversity showing amino acid and length polymorphism, both within and between parasite isolates. The generation of Ta SP diversity may allow the evasion of host immunity by the parasite since Ta SP is a highly antigenic parasite protein.