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Advances in the Management of Pediatric Central Nervous System Tumors
Author(s) -
Abdullah Shaker,
Qaddoumi Ibrahim,
Bouffet Eric
Publication year - 2008
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1414.005
Subject(s) - subspecialty , medicine , neurosurgery , intensive care medicine , radiation oncology , modalities , radiation therapy , multidisciplinary approach , treatment modality , radiosurgery , pathology , surgery , social science , sociology
Central nervous system tumors are the most common pediatric solid tumors and a leading cause of cancer‐related mortality and morbidity in this age group. Survival rates have improved significantly over the last decades for most of the tumor types, as a consequence of improvements in neuroimaging, neurosurgery and neuroanesthesia, radiation oncology, and medical oncology. The complexity of the management of these patients requires a multidisciplinary approach and has led to the emergence of a new subspecialty of pediatric neuro‐oncologists who are dedicated to the management and follow‐up of this population. This review highlights the most critical advances in the diagnostic and treatment modalities of pediatric brain tumors. A specific review of the most common tumor types discusses treatment options, controversies, and ongoing developments, with an emphasis on cooperative trials.