Effector Memory CD8 +  T Cells Are Resistant to Apoptosis | Zendy

GUPTA SUDHIR | Zendy; GOLLAPUDI SASTRY | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Effector Memory CD8 + T Cells Are Resistant to Apoptosis

Author(s) -

GUPTA SUDHIR,

GOLLAPUDI SASTRY

Publication year - 2007

Publication title -

annals of the new york academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.712

H-Index - 248

eISSN - 1749-6632

pISSN - 0077-8923

DOI - 10.1196/annals.1398.017

Subject(s) - effector , cytotoxic t cell , apoptosis , cd8 , microbiology and biotechnology , biology , immunology , chemistry , immune system , genetics , in vitro

: Based upon their migrating properties and effector functions, CD8 + T cells have been further classified into central memory (T CM ) and two types of effector memory (T EM and T EMRA ) cells. These memory cells display distinct replicative characteristics. Because apoptosis plays an important role in cellular homeostasis, we have examined the relative sensitivity of naïve (T N ) and different memory CD8 + T cells to apoptosis. We show that both T EM and T EMRA CD8 + T cells are resistant to apoptosis, whereas T N and T CM CD8 + T cells are sensitive to apoptosis.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research