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Rapid Quantitative Chairside Test for Active MMP‐8 in Gingival Crevicular Fluid
Author(s) -
PRESCHER N,
MAIER K,
MUNJAL S. K.,
SORSA T.,
BAUERMEISTER C.D,
STRUCK F,
NETUSCHIL L
Publication year - 2007
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1384.019
Subject(s) - periodontist , dentistry , matrix metalloproteinase , medicine , periodontitis , orthodontics
: In a first pilot field study 64 gingival crevicular fluid (GCF) samples were collected from patients of dental practitioners. The dentists (one orthodontist one periodontist, and one general practitioner) were asked to monitor the respective clinical status of the sites of sampling and to collect, if possible, sulcus fluid samples from healthy as well as affected sites from the same patient. The concentration of activated matrix metalloproteinase‐8 (aMMP‐8) in the GCF was recorded using a set of monoclonal antibodies and a novel Dento Analyzer . From all three dental offices the distribution of the aMMP‐8 values in GCF showed a congruent pattern, where healthy and periodontitis‐affected inflamed sites were clearly disparate.