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Mucormycosis Mimicks Sinusitis in a Diabetic Adult
Author(s) -
SZALAI GYÖRGY,
FELLEGI VERONIKA,
SZABÓ ZSUZSANNA,
VITÉZ LAJOS CSOKONAI
Publication year - 2006
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1372.010
Subject(s) - mucormycosis , medicine , sinusitis , pharmacology , intensive care medicine , immunology , surgery
Fungal sinusitis caused by invasive fungal infections, such as Mucormycosis , occurs predominantly in an immunocompromised patient. However, invasive cranial bone mycoses are rare and are usually associated with host immunodeficiency. They are difficult to diagnose, and in many cases are fatal. Treatment consists of antifungal chemotherapy, radical surgical debridement, and control of the underlying immunological condition. We report a case of Mucormycosis in a patient with type 1 diabetes mellitus. The patient had a history of dental pathology and associated renal dysfunction. The patient was managed by extensive surgical debridement followed by amphotericin B lipid complex injection (Abelcet 5 mg/bw kg/day) as an antifungal agent. Our patient's ocular function was affected. The radical treatment and follow‐up by a multidisciplinary team eliminated the mucor‐related consequences, however, the patient died because of end‐stage renal failure. In conclusion, type 1 diabetes may be associated with invasive fungal sinusitis.