Oocyte Maturation in Assisted Reproductive Techniques | Zendy

LOUTRADIS DIMITRIS | Zendy; KIAPEKOU ERASMIA | Zendy; ZAPANTI EVANGELIA | Zendy; ANTSAKLIS ARISTIDIS | Zendy

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Oocyte Maturation in Assisted Reproductive Techniques

Author(s) -

LOUTRADIS DIMITRIS,

KIAPEKOU ERASMIA,

ZAPANTI EVANGELIA,

ANTSAKLIS ARISTIDIS

Publication year - 2006

Publication title -

annals of the new york academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.712

H-Index - 248

eISSN - 1749-6632

pISSN - 0077-8923

DOI - 10.1196/annals.1365.020

Subject(s) - germinal vesicle , oocyte , in vitro maturation , polar body , human fertilization , microbiology and biotechnology , embryogenesis , biology , andrology , embryo , anatomy , medicine

Human oocyte maturation is a long process during which nuclear maturation occurs resulting in germinal vesicle breakdown (transition from prophase I to metaphase II) and extrusion of the first polar body. During oocyte maturation, in parallel with nuclear maturation, a number of events take place in the oocyte cytoplasm that assist fertilization and early embryonic development. So far several attempts have been made to mature human oocytes in vitro . The main patient group to which in vitro maturation (IVM) has been applied is polycystic ovarian syndrome. In a concise review we present the techniques used for the IVM of oocytes and the role of hormones and growth factors in IVM and subsequent fertilization and early embryonic development.

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