Premium
Activity of Telithromycin against Thirteen New Isolates of C. burnetii Including Three Resistant to Doxycycline
Author(s) -
ROLAIN JEANMARC,
LAMBERT FRÉDÉRIC,
RAOULT DIDIER
Publication year - 2005
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1355.039
Subject(s) - telithromycin , doxycycline , virology , q fever , coxiella burnetii , microbiology and biotechnology , medicine , biology , antibiotics , antibacterial agent
A bstract : In this study we have evaluated the in vitro activity of antibiotics against 13 new isolates of Coxiella burnetii using a real‐time quantitative PCR assay. MICs against doxycycline ranged from 1 to 8 μg/mL, telithromycin from 0.5 to 2 μg/mL, and all strains had MICs ≥ 8 μg/mL for erythromycin. We report that strains resistant to doxycycline exist either in humans or animals.