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RNA Regulation in Mammals
Author(s) -
SZYMANSKI MACIEJ,
BARCISZEWSKI JAN
Publication year - 2006
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1354.066
Subject(s) - multicellular organism , non coding rna , biology , rna , gene , regulation of gene expression , computational biology , gene expression , microrna , genetics , long non coding rna , evolutionary biology
Noncoding RNAs (ncRNA) are ubiquitous regulatory factors affecting gene expression in all organisms. In eukaryotes ncRNAs have been shown to operate on virtually every level of transmission of genetic information. They are implicated in processes that are crucial for the correct growth and development of multicellular organisms. Changes in their expression are often related to stress conditions or associated with diseases or developmental disorders.