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Determinants of Low EPSP Attenuation in Primary Dendrites of Mitral Cells: Modeling Study
Author(s) -
POPOVIĆ MARKO,
DJURIŠIĆ MAJA,
ZEČEVIĆ DEJAN
Publication year - 2005
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1342.033
Subject(s) - attenuation , excitatory postsynaptic potential , intracellular , patch clamp , biophysics , membrane potential , materials science , chemistry , electrophysiology , neuroscience , biology , physics , optics , biochemistry , inhibitory postsynaptic potential
A bstract : Efficiency of synaptic potential propagation through neurons depends mainly on their membrane properties and intracellular resistivity. We use a morphologically realistic compartmental model of a mitral cell and data obtained from whole‐cell patch‐clamp and voltage‐imaging experiments to explore passive parameter space in which reported low EPSP attenuation is observed.