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Labeling Studies on the Formation Pathway of N ε ‐Carboxymethyllysine in Maillard‐type Reactions
Author(s) -
KASPER MARTINA,
SCHIEBERLE PETER
Publication year - 2005
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1333.007
Subject(s) - maillard reaction , glycation , chemistry , autoxidation , glyoxal , advanced glycation end product , biochemistry , organic chemistry , receptor
A bstract : N ε ‐carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon‐13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.