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Effect of Cortisol on Aquaporin Expression in the Esophagus of the European Eel, Anguilla anguilla
Author(s) -
MARTINEZ ANNESOPHIE,
WILSON GILLIAN,
PHILLIPS CLAIRE,
CUTLER CHRISTOPHER,
HAZON NEIL,
CRAMB GORDON
Publication year - 2005
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1327.072
Subject(s) - aquaporin , acclimatization , downregulation and upregulation , endocrinology , aquaporin 1 , medicine , aquaporin 2 , biology , chemistry , gene isoform , fresh water , andrology , seawater , fishery , water channel , microbiology and biotechnology , biochemistry , ecology , gene , oceanography , geology , inlet
A bstract : Long‐term cortisol infusion into freshwater (FW)‐adapted eels induced a significant increase in aquaporin‐1 (AQP1) mRNA expression within the esophageal epithelium of migratory “silver” eels, but not in nonmigratory, immature “yellow” eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin‐1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.