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Androgen Receptor in the Ovary of Postnatal Bank Vole Females
Author(s) -
GALAS JERZY,
SLOMCZYNSKA MARIA,
KWASNIK ANNA
Publication year - 2005
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1327.050
Subject(s) - photoperiodism , ovary , endocrinology , medicine , androgen receptor , bank vole , androgen , biology , follicular phase , antral follicle , vole , follicular fluid , receptor , hormone , oocyte , cancer , embryo , population , environmental health , prostate cancer , microbiology and biotechnology
A bstract : In this experiment, we investigated the influence of the photoperiod upon androgen receptor (AR) distribution and steroid concentrations in ovaries of 21‐day‐old bank vole females. Sections (6 μm) were assayed immunohistochemically. ARs were localized in the nuclei of granulosa cells. The strongest immunoreaction was observed in primary and early antral follicles, and declined during follicular development. P 4 , A, and E 2 contents were measured by RIAs in ovarian homogenates from animals kept in two photoperiods. Ovaries of animals kept in a long photoperiod (18:6 light:dark), which stimulates gonadal activity, contained more P 4 than those kept in a short one (6:18 light:dark). There was no difference in levels of A and E 2 .