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Interaction of PCBs with Thyroid Hormone Levels and Time of Hatching in Chicken Embryos
Author(s) -
BECK V.,
ROELENS S A,
MAERVOET J,
SCHEPENS P,
DARRAS V.M
Publication year - 2005
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1327.029
Subject(s) - hatching , thyroid , embryo , hormone , endocrinology , medicine , thyroid hormones , intracellular , embryogenesis , triiodothyronine , chemistry , zoology , biology , andrology , biochemistry , fishery
A bstract : The effects of polychlorinated biphenyls (PCB 77, PCB 153, and the mixture Aroclor 1242) on circulating and intracellular thyroid hormone (TH) levels were studied during chicken embryonic development. We observed no influences of PCB 153 on TH availability. Aroclor 1242 caused a transient increase in the T 3 level in the cerebellum at day 16. Clear effects were only seen with PCB 77 around the period of hatching: a severely reduced TH peak, which normally coincides with the stage of internal pipping, and a considerable delay in the moment of hatching.