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Toll‐Like Receptor Expression and Response to Specific Stimulation in Adipocytes and Preadipocytes
Author(s) -
PIETSCH J.,
BATRA A.,
STROH T.,
FEDKE I.,
GLAUBEN R.,
OKUR B.,
ZEITZ M.,
SIEGMUND B.
Publication year - 2006
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1326.021
Subject(s) - adipose tissue , stimulation , innate immune system , toll like receptor , receptor , adipocyte , cytokine , biology , endocrinology , medicine , immunology , microbiology and biotechnology
Data in this study indicate that both adipocytes and preadipocytes express abroad set of TLRs and they also respond to specific stimulation by cytokine production. The may be of relevance to Crohn's disease and a suggests a closer link between adipose tissue and innate immunity.