Transcession of DNA from Bacteria to Human Cells in Culture: A Possible Role in Oncogenesis | Zendy

ANKER PHILIPPE | Zendy; ZAJAC VLADIMIR | Zendy; LYAUTEY JACQUELINE | Zendy; LEDERREY CHRISTINE | Zendy; DUNAND CHRISTOPHE | Zendy; LEFORT FRANÇOIS | Zendy; MULCAHY HUGH | Zendy; HEINEMANN JACK | Zendy; STROUN MAURICE | Zendy

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Transcession of DNA from Bacteria to Human Cells in Culture: A Possible Role in Oncogenesis

Author(s) -

ANKER PHILIPPE,

ZAJAC VLADIMIR,

LYAUTEY JACQUELINE,

LEDERREY CHRISTINE,

DUNAND CHRISTOPHE,

LEFORT FRANÇOIS,

MULCAHY HUGH,

HEINEMANN JACK,

STROUN MAURICE

Publication year - 2004

Publication title -

annals of the new york academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.712

H-Index - 248

eISSN - 1749-6632

pISSN - 0077-8923

DOI - 10.1196/annals.1318.030

Subject(s) - bacteria , bacillus subtilis , organism , microorganism , dna , biology , microbiology and biotechnology , cell culture , polymerase chain reaction , carcinogenesis , gene , hl60 , genetics

A bstract : The human organism is continuously in close contact with microorganisms, especially bacteria. In the present work, by means of a real‐time polymerase chain reaction (PCR) technique, we looked for the presence of a distinct bacterial gene in human cells. To this end, we cultured a human cell line, HL60, in a supernatant in which bacteria ( Bacillus subtilis ) had been grown. A transient transcession of bacterial DNA into the human cells was observed.

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