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Effects of Pituitary Adenylate Cyclase‐Activating Polypeptide and Vasoactive Intestinal Polypeptide on Food Intake and Locomotor Activity in the Goldfish, Carassius auratus
Author(s) -
MATSUDA KOUHEI,
MARUYAMA KEISUKE,
NAKAMACHI TOMOYA,
MIURA TOHRU,
SHIODA SEIJI
Publication year - 2006
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1317.054
Subject(s) - carassius auratus , vasoactive intestinal peptide , adenylate kinase , medicine , endocrinology , cyclase , vasoactive , chemistry , food intake , biology , neuropeptide , fish <actinopterygii> , fishery , stimulation , receptor
We investigated the effects of intracerebroventricular (ICV) and intraperitoneal (IP) administration of pituitary adenylate cyclase‐activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) on food intake in the goldfish, Carassius auratus . Cumulative food intake was significantly decreased by ICV injection of PACAP or VIP. Similarly, IP administration of PACAP or VIP induced a significant decrease in food intake. ICV injection of PACAP or VIP also induced a significant decrease in locomotor activity. These results suggest that PACAP and VIP may be involved in the regulation of feeding in goldfish.