Premium
Presence of PACAP and VIP in Embryonic Chicken Brain
Author(s) -
JOZSA RITA,
HOLLOSY TIBOR,
NEMETH JOZSEF,
TAMÁS ANDREA,
LUBICS ANDREA,
JAKAB BALAZS,
OLAH ANDRAS,
ARIMURA AKIRA,
REGLÖDI DORA
Publication year - 2006
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1317.039
Subject(s) - vasoactive intestinal peptide , cerebrum , radioimmunoassay , endocrinology , medicine , hypothalamus , neuropeptide , cerebellum , adenylate kinase , hatching , embryonic stem cell , biology , embryo , pituitary adenylate cyclase activating peptide , cyclase , stimulation , chemistry , central nervous system , microbiology and biotechnology , receptor , biochemistry , gene , zoology
The aim of the present article was to investigate the occurrence and temporary changes of pituitary adenylate cyclase‐activating polypeptide (PACAP)‐38 and vasoactive intestinal peptide (VIP) in various brain areas of chicken embryos by means of radioimmunoassay. The highest concentrations of PACAP‐38 were measured in the brain stem followed by the hypothalamus, cerebellum, and telencephalon. PACAP‐38 levels were significantly higher than those of VIP in all examined brain areas. The levels of both PACAP‐38 and VIP showed a tendency to decrease until hatching during embryonic development of the chicken.