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The Effects of PACAP and VIP on the in Vitro Melatonin Secretion from the Embryonic Chicken Pineal Gland
Author(s) -
FALUHELYI N.,
REGL?DI D.,
CSERNUS V.
Publication year - 2006
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1317.025
Subject(s) - melatonin , pineal gland , secretion , endocrinology , medicine , embryonic stem cell , in vitro , biology , chemistry , microbiology and biotechnology , biochemistry , gene
The effects of in vitro VIP administration and those of in ovo pretreatment with PACAP antagonist (PACAP6‐38) on the development of the embryonic melatonin (MT) secretion were investigated. With dynamic in vitro bioassay we showed that (1) the development of the circadian MT secretion seems to be unaffected by VIP administrations or by PACAP6‐38 pretreatments; (2) exposure of the embryonic chicken pineal gland to VIP induces transitory increase in MT secretion at or before the 14th embryonic day in vitro .