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Longitudinal Effect of Olanzapine on Fasting Serum Lipids: A Randomized, Prospective, 4‐Month Study
Author(s) -
KI BRUCE J.,
LIUSEIFERT HONG,
AHL JONNA,
AHMED SAEEDUDDIN,
BAKER ROBERT W.
Publication year - 2004
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1314.043
Subject(s) - olanzapine , blood lipids , medicine , randomized controlled trial , prospective cohort study , endocrinology , cholesterol , schizophrenia (object oriented programming) , psychiatry
A bstract : Our objective was to compare lipid profiles of schizophrenic patients treated with conventional antipsychotics or risperidone to those of patients switched to olanzapine. Our results indicate that in patients switched to olanzapine, fasting serum lipids initially increased then returned to pretreatment levels, and endpoint lipid levels were not significantly different from those in patients remaining on conventional antipsychotics or risperidone.